Peficitinib (ASP015K, JNJ-54781532)

Catalog No. A14438

Peficitinib (ASP015K,JNJ-54781532)是一种新型的强力JAK抑制剂，在佐剂诱导的大鼠关节炎模型中显示出强效功效。

Technical details

Catalog Num	A14438
M. Wt	326.39
Formula	C18H22N4O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	944118-01-8
Synonyms	ASP015K, JNJ-54781532
SMILES	C1C2CC3CC(C2)(CC1C3NC4=C5C=CNC5=NC=C4C(=O)N)O

Biological Activity

Peficitinib (ASP015K,JNJ-54781532)是一种新型的强力JAK抑制剂，在佐剂诱导的大鼠关节炎模型中显示出强效功效。

Targets

JAK

Solubility *

In vitro	DMSO	58 mg/mL (177.69 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	30.64 mL	153.19 mL	306.38 mL
0.5 mM	6.13 mL	30.64 mL	61.28 mL
1 mM	3.06 mL	15.32 mL	30.64 mL
5 mM	0.61 mL	3.06 mL	6.13 mL

*The above data is based on the productmolecular weight 326.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.