Acalisib (GS-9820)

Catalog No. A14441

Acalisib (GS-9820)是IA类磷酸肌醇3激酶(PI3K)的110 kDa催化亚基的β和δ异构体的抑制剂,具有潜在的免疫调节和抗肿瘤活性。
Catalog Num A14441
M. Wt 401.4
Formula C21H16FN7O
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 870281-34-8
Synonyms GS-9820
SMILES CC(C1=NC2=C(C=C(C=C2)F)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5
Acalisib (GS-9820)是IA类磷酸肌醇3激酶(PI3K)的110 kDa催化亚基的β和δ异构体的抑制剂,具有潜在的免疫调节和抗肿瘤活性。
In vitro DMSO 76 mg/mL (189.34 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.91 mL 124.56 mL 249.13 mL
0.5 mM 4.98 mL 24.91 mL 49.83 mL
1 mM 2.49 mL 12.46 mL 24.91 mL
5 mM 0.5 mL 2.49 mL 4.98 mL

*The above data is based on the productmolecular weight 401.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.