SP2509 (HCI-2509)
Catalog No. A14443
SP2509 (HCI-2509)是一种新型组蛋白脱甲基酶LSD1(KDM1A)拮抗剂,IC50为13 nM。对MAO-A和MAO-B没有抑制作用。
Catalog Num | A14443 |
---|---|
M. Wt | 437.9 |
Formula | C19H20ClN3O5S |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1423715-09-6 |
Synonyms | SP-2509 |
SMILES | CC(=C1C=C(C=CC1=O)Cl)NNC(=O)C2=CC(=CC=C2)S(=O)(=O)N3CCOCC3 |
SP2509 (HCI-2509)是一种新型组蛋白脱甲基酶LSD1(KDM1A)拮抗剂,IC50为13 nM。对MAO-A和MAO-B没有抑制作用。
Targets
LSD1 | ||||
13 nM |
In vitro (25°C) | DMSO | 36 mg/mL (82.2 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 10% DMSO+corn oil | 4 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.84 mL | 114.18 mL | 228.36 mL |
0.5 mM | 4.57 mL | 22.84 mL | 45.67 mL |
1 mM | 2.28 mL | 11.42 mL | 22.84 mL |
5 mM | 0.46 mL | 2.28 mL | 4.57 mL |
*The above data is based on the productmolecular weight 437.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.