Bosentan Hydrate
Catalog No. A14944
Bosentan Hydrate是ET-A和ET-B的内皮素（ET）受体拮抗剂，Ki分别为4.7 nM和95 nM。
| Catalog Num | A14944 |
|---|---|
| M. Wt | 569.63 |
| Formula | C27H29N5O6S.H2O |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 157212-55-0 |
| Synonyms | Ro 47-0203 |
| SMILES | CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4OC.O |
Bosentan Hydrate是ET-A和ET-B的内皮素（ET）受体拮抗剂，Ki分别为4.7 nM和95 nM。
| In vitro (25°C) | DMSO | 92 mg/mL (161.51 mM) | |
| Water | Insoluble | ||
| Ethanol | 2 mg/mL (3.51 mM) | ||
| In vivo | 2% DMSO+30% PEG 300+2% Tween 80+ddH2O | 4 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.56 mL | 87.78 mL | 175.55 mL |
| 0.5 mM | 3.51 mL | 17.56 mL | 35.11 mL |
| 1 mM | 1.76 mL | 8.78 mL | 17.56 mL |
| 5 mM | 0.35 mL | 1.76 mL | 3.51 mL |
*The above data is based on the productmolecular weight 569.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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