AST 487

Catalog No. A15003

AST487是Ret激酶抑制剂/FLT3抑制剂,对Ret的IC50为0.88 uM。
Catalog Num A15003
M. Wt 529.56
Formula C26H30F3N7O2
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 630124-46-8
Synonyms NVP-AST 487
SMILES CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)NC3=CC=C(C=C3)OC4=NC=NC(=C4)NC)C(F)(F)F
AST487是Ret激酶抑制剂/FLT3抑制剂,对Ret的IC50为0.88 uM。
In vitro DMSO 89 mg/mL (168.06 mM)
Water Insoluble
Ethanol 29 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.88 mL 94.42 mL 188.84 mL
0.5 mM 3.78 mL 18.88 mL 37.77 mL
1 mM 1.89 mL 9.44 mL 18.88 mL
5 mM 0.38 mL 1.89 mL 3.78 mL

*The above data is based on the productmolecular weight 529.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.