AZD1152

Catalog No. A15011

AZD1152是一种前药,可在血清中迅速经历磷酸酶介导的裂解作用,释放出Barasertib-hQPA(一种选择性的Aurora B激酶抑制剂),在急性髓细胞性白血病(AML)患者的临床研究中显示出初步活性。
Catalog Num A15011
M. Wt 587.54
Formula C26H31FN7O6P
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 722543-31-9
Synonyms Barasertib, AZD-1152, AZD 1152
SMILES CCN(CCCOC1=CC2=C(C=C1)C(=NC=N2)NC3=NNC(=C3)CC(=O)NC4=CC(=CC=C4)F)CCOP(=O)(O)O
AZD1152是一种前药,可在血清中迅速经历磷酸酶介导的裂解作用,释放出Barasertib-hQPA(一种选择性的Aurora B激酶抑制剂),在急性髓细胞性白血病(AML)患者的临床研究中显示出初步活性。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.02 mL 85.1 mL 170.2 mL
0.5 mM 3.4 mL 17.02 mL 34.04 mL
1 mM 1.7 mL 8.51 mL 17.02 mL
5 mM 0.34 mL 1.7 mL 3.4 mL

*The above data is based on the productmolecular weight 587.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.