Baricitinib phosphate

Catalog No. A15014

Baricitinib phosphate是一种选择性的JAK1和JAK2抑制剂，IC50为5.9 nM和5.7 nM，选择性是JAK3和Tyk2的?70和?10倍，对c-Met和Chk2没有抑制作用。

Technical details

Catalog Num	A15014
M. Wt	469.41
Formula	C16H20N7O6PS
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1187595-84-1
Synonyms	INCB 028050, LY 3009104, INCB028050, LY3009104, LY-3009104, INCB-028050
SMILES	CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O

Biological Activity

Baricitinib phosphate是一种选择性的JAK1和JAK2抑制剂，IC50为5.9 nM和5.7 nM，选择性是JAK3和Tyk2的?70和?10倍，对c-Met和Chk2没有抑制作用。

Solubility *

In vitro	DMSO	85 mg/mL (181.08 mM)
	Water
	Ethanol
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.3 mL	106.52 mL	213.03 mL
0.5 mM	4.26 mL	21.3 mL	42.61 mL
1 mM	2.13 mL	10.65 mL	21.3 mL
5 mM	0.43 mL	2.13 mL	4.26 mL

*The above data is based on the productmolecular weight 469.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Baricitinib phosphate

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions