BAY 61-3606 dihydrochloride

Catalog No. A15017

BAY 61-3606 dihydrochloride是一种有效的Syk激酶抑制剂（Ki = 7.5 nM）。

Technical details

Catalog Num	A15017
M. Wt	463.32
Formula	C20H20Cl2N6O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	648903-57-5
Synonyms	BAY61-3606, BAY-61-3606, BAY-613606
SMILES	COC1=C(C=C(C=C1)C2=CC3=NC=CN3C(=N2)NC4=C(C=CC=N4)C(=O)N)OC.Cl.Cl

Biological Activity

BAY 61-3606 dihydrochloride是一种有效的Syk激酶抑制剂（Ki = 7.5 nM）。

Targets

Syk
7.5 nM(Ki)

Solubility *

In vitro	DMSO	14 mg/mL (30.21 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.58 mL	107.92 mL	215.83 mL
0.5 mM	4.32 mL	21.58 mL	43.17 mL
1 mM	2.16 mL	10.79 mL	21.58 mL
5 mM	0.43 mL	2.16 mL	4.32 mL

*The above data is based on the productmolecular weight 463.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.