Bitopertin

Catalog No. A15021

Bitopertin是一种有效的非竞争性甘氨酸再摄取抑制剂（GlyT1）。

Technical details

Catalog Num	A15021
M. Wt	543.46
Formula	C21H20F7N3O4S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	845614-11-1
Synonyms	RG1678, RO4917838, RG-1678, RG 1678, RO-4917838, RO 4917838
SMILES	C[C@@H](C(F)(F)F)OC1=C(C=C(C=C1)S(=O)(=O)C)C(=O)N2CCN(CC2)C3=C(C=C(C=N3)C(F)(F)F)F

Biological Activity

Bitopertin是一种有效的非竞争性甘氨酸再摄取抑制剂（GlyT1）。

Targets

GlyT1
25nM

Solubility *

In vitro	DMSO	89 mg/mL (163.76 mM)
	Water	Insoluble
	Ethanol	89 mg/mL (163.76 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.4 mL	92 mL	184.01 mL
0.5 mM	3.68 mL	18.4 mL	36.8 mL
1 mM	1.84 mL	9.2 mL	18.4 mL
5 mM	0.37 mL	1.84 mL	3.68 mL

*The above data is based on the productmolecular weight 543.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.