Cobimetinib (racemate)
Catalog No. A15050
Cobimetinib (racemate)是一种有效的，高度选择性的MEK1/2抑制剂。
- Yuki Shimizu, .et al. Acquired resistance to BRAF inhibitors is mediated by BRAF splicing variants in BRAF V600E mutation-positive colorectal neuroendocrine carcinoma, Cancer Lett, 2022, Sep 1;543 PMID: 35724767
- Chun-Yu Liu, .et al. Varlitinib Downregulates HER/ERK Signaling and Induces Apoptosis in Triple Negative Breast Cancer Cells, Cancers (Basel), 2019, Jan 17;11(1) PMID: 30658422
| Catalog Num | A15050 |
|---|---|
| M. Wt | 531.31 |
| Formula | C21H21F3IN3O2 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 934662-91-6 |
| Synonyms | GDC-0973 racemate, XL-518, GDC 0973, XL 518, GDC0973, XL518 |
| SMILES | C1CCNC(C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O |
Cobimetinib (racemate)是一种有效的，高度选择性的MEK1/2抑制剂。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.82 mL | 94.11 mL | 188.21 mL |
| 0.5 mM | 3.76 mL | 18.82 mL | 37.64 mL |
| 1 mM | 1.88 mL | 9.41 mL | 18.82 mL |
| 5 mM | 0.38 mL | 1.88 mL | 3.76 mL |
*The above data is based on the productmolecular weight 531.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Contact information
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: sales@adooq.com
ADOOQ 产品质量保证
We promise all products to perform as described.