Docetaxel Trihydrate

Catalog No. A15070

Docetaxel Trihydrate是紫杉醇的类似物，是通过与稳定的微管结合而抑制微管解聚的抑制剂。

Product Citations

Ogawa C, .et al. Comparison of Chemical Behavior of Original and Generic Docetaxel Formulations as Non-alcoholic Preparations: Discussion about Diluent Solvents for Docetaxel, Yakugaku Zasshi, 2018, 138(7):973-984 PMID: 29962477

Technical details

Catalog Num	A15070
M. Wt	861.93
Formula	C43H59NO17
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	148408-66-6
Synonyms	Taxotere Trihydrate
SMILES	CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O.O.O.O

Biological Activity

Docetaxel Trihydrate是紫杉醇的类似物，是通过与稳定的微管结合而抑制微管解聚的抑制剂。

Solubility *

In vitro	DMSO	98 mg/mL (113.69 mM)
	Water	Insoluble
	Ethanol	98 mg/mL (113.69 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	11.6 mL	58.01 mL	116.02 mL
0.5 mM	2.32 mL	11.6 mL	23.2 mL
1 mM	1.16 mL	5.8 mL	11.6 mL
5 mM	0.23 mL	1.16 mL	2.32 mL

*The above data is based on the productmolecular weight 861.93. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.