GSK256066 2,2,2-trifluoroacetic acid

Catalog No. A15097

GSK256066是一种选择性PDE4B(与A-D型同等亲和力)抑制剂,IC50为3.2 pM,对PDE1/2/3/5/6的选择性> 380,000倍,对PDE4B与PDE7的选择性> 2500倍。
Catalog Num A15097
M. Wt 632.61
Formula C29H27F3N4O7S
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1415560-64-3
Synonyms GSK-256066, GSK 256066
SMILES CC1=C2C(=CC(=C1)S(=O)(=O)C3=CC=CC(=C3)C(=O)N(C)C)C(=C(C=N2)C(=O)N)NC4=CC(=CC=C4)OC.C(=O)(C(F)(F)F)O
GSK256066是一种选择性PDE4B(与A-D型同等亲和力)抑制剂,IC50为3.2 pM,对PDE1/2/3/5/6的选择性> 380,000倍,对PDE4B与PDE7的选择性> 2500倍。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.81 mL 79.04 mL 158.08 mL
0.5 mM 3.16 mL 15.81 mL 31.62 mL
1 mM 1.58 mL 7.9 mL 15.81 mL
5 mM 0.32 mL 1.58 mL 3.16 mL

*The above data is based on the productmolecular weight 632.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.