GW3965
Catalog No. A15100
GW3965是hLXRα和hLXRβ的有效选择性LXR激动剂，EC50分别为190和30 nM。
- B Dong ,etc. High-fructose diet downregulates long-chain acyl-CoA synthetase 3 expression in liver of hamsters via impairing LXR/RXR signaling pathway. Journal of lipid research, 2013, 54(5), 1241-1254.
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| Catalog Num | A15100 |
|---|---|
| M. Wt | 582.05 |
| Formula | C33H31ClF3NO3 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 405911-09-3 |
| Synonyms | GW 3965, GW-3965 |
| SMILES | C1=CC=C(C=C1)C(CN(CCCOC2=CC=CC(=C2)CC(=O)O)CC3=C(C(=CC=C3)C(F)(F)F)Cl)C4=CC=CC=C4 |
GW3965是hLXRα和hLXRβ的有效选择性LXR激动剂，EC50分别为190和30 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.18 mL | 85.9 mL | 171.81 mL |
| 0.5 mM | 3.44 mL | 17.18 mL | 34.36 mL |
| 1 mM | 1.72 mL | 8.59 mL | 17.18 mL |
| 5 mM | 0.34 mL | 1.72 mL | 3.44 mL |
*The above data is based on the productmolecular weight 582.05. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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