LDK378 (Ceritinib) dihydrochloride
Catalog No. A15142
LDK378 (Ceritinib) dihydrochloride是有效的抗ALK抑制剂，IC50为0.2 nM，对IGF-1R和InsR的选择性分别为40倍和35倍。
| Catalog Num | A15142 |
|---|---|
| M. Wt | 594.6 |
| Formula | C28H37Cl2N5O3S |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1380575-43-8 |
| Synonyms | LDK 378 dihydrochloride, LDK-378 dihydrochloride, Ceritinib dihydrochloride |
| SMILES | CC1=CC(=C(C=C1C2CCNCC2)OC(C)C)NC3=NC=C(C(=N3)NC4=CC=CC=C4S(=O)(=O)C(C)C)Cl.Cl.Cl |
LDK378 (Ceritinib) dihydrochloride是有效的抗ALK抑制剂，IC50为0.2 nM，对IGF-1R和InsR的选择性分别为40倍和35倍。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.82 mL | 84.09 mL | 168.18 mL |
| 0.5 mM | 3.36 mL | 16.82 mL | 33.64 mL |
| 1 mM | 1.68 mL | 8.41 mL | 16.82 mL |
| 5 mM | 0.34 mL | 1.68 mL | 3.36 mL |
*The above data is based on the productmolecular weight 594.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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