MK-0591 (Quiflapon)

Catalog No. A15163

MK-0591 (Quiflapon)是一种选择性的特异性5-脂氧合酶激活蛋白(FLAP)抑制剂,在FLAP结合测定中的IC50值为1.6 nM。
  • MA Sartim, .et al. Crotoxin-Induced Mice Lung Impairment: Role of Nicotinic Acetylcholine Receptors and COX-Derived Prostanoids, Biomolecules, 2020, May; 10(5): 794 PMID: 32443924
Catalog Num A15163
M. Wt 587.17
Formula C34H35ClN2O3S
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 136668-42-3
Synonyms Quiflapon, MK0591, MK 0591
SMILES CC(C)(C)SC1=C(N(C2=C1C=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)CC5=CC=C(C=C5)Cl)CC(C)(C)C(=O)O
MK-0591 (Quiflapon)是一种选择性的特异性5-脂氧合酶激活蛋白(FLAP)抑制剂,在FLAP结合测定中的IC50值为1.6 nM。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.03 mL 85.15 mL 170.31 mL
0.5 mM 3.41 mL 17.03 mL 34.06 mL
1 mM 1.7 mL 8.52 mL 17.03 mL
5 mM 0.34 mL 1.7 mL 3.41 mL

*The above data is based on the productmolecular weight 587.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.