NVP-BKM120 Hydrochloride
Catalog No. A15195
NVP-BKM120 Hydrochloride是p110α/β/δ/γ的选择性PI3K抑制剂，IC50分别为52 nM/166 nM/116 nM/262 nM。对VPS34，mTOR，DNA-PK的效力降低，对PI4Kβ几乎没有活性。
| Catalog Num | A15195 |
|---|---|
| M. Wt | 446.85 |
| Formula | C18H21F3N6O2.HCl |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1312445-63-8 |
| Synonyms | BKM-120 hydrochloride, BKM120 hydrochloride, BKM 120 hydrochloride |
| SMILES | C1COCCN1C2=NC(=NC(=C2)C3=CN=C(C=C3C(F)(F)F)N)N4CCOCC4.Cl |
NVP-BKM120 Hydrochloride是p110α/β/δ/γ的选择性PI3K抑制剂，IC50分别为52 nM/166 nM/116 nM/262 nM。对VPS34，mTOR，DNA-PK的效力降低，对PI4Kβ几乎没有活性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.38 mL | 111.89 mL | 223.79 mL |
| 0.5 mM | 4.48 mL | 22.38 mL | 44.76 mL |
| 1 mM | 2.24 mL | 11.19 mL | 22.38 mL |
| 5 mM | 0.45 mL | 2.24 mL | 4.48 mL |
*The above data is based on the productmolecular weight 446.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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