PF-04457845

Catalog No. A15209

PF-04457845是一种强效且选择性强的FAAH抑制剂,IC50为7.2 nM,在动物研究中的镇痛和抗炎作用均与萘普生相当。
Catalog Num A15209
M. Wt 455.43
Formula C23H20F3N5O2
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1020315-31-4
Synonyms PF 04457845, PF04457845
SMILES C1CN(CCC1=CC2=CC(=CC=C2)OC3=NC=C(C=C3)C(F)(F)F)C(=O)NC4=NN=CC=C4
PF-04457845是一种强效且选择性强的FAAH抑制剂,IC50为7.2 nM,在动物研究中的镇痛和抗炎作用均与萘普生相当。
In vitro DMSO 90 mg/mL (197.61 mM)
Water Insoluble
Ethanol 4 mg/mL (8.78 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.96 mL 109.79 mL 219.57 mL
0.5 mM 4.39 mL 21.96 mL 43.91 mL
1 mM 2.2 mL 10.98 mL 21.96 mL
5 mM 0.44 mL 2.2 mL 4.39 mL

*The above data is based on the productmolecular weight 455.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.