Teneligliptin hydrobromide

Catalog No. A15258

Teneligliptin hydrobromide是一种新颖，有效且持久的二肽基肽酶-4抑制剂。在体外竞争性抑制人血浆，大鼠血浆和人重组DPP-4，IC50值约为1 nM。

Technical details

Catalog Num	A15258
M. Wt	1257.72
Formula	C44H65Br5N12O2S2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	906093-29-6
Synonyms
SMILES	CC1=NN(C(=C1)N2CCN(CC2)C3CC(NC3)C(=O)N4CCSC4)C5=CC=CC=C5.CC1=NN(C(=C1)N2CCN(CC2)C3CC(NC3)C(=O)N4CCSC4)C5=CC=CC=C5.Br.Br.Br.Br.Br

Biological Activity

Teneligliptin hydrobromide是一种新颖，有效且持久的二肽基肽酶-4抑制剂。在体外竞争性抑制人血浆，大鼠血浆和人重组DPP-4，IC50值约为1 nM。

Targets

Dipeptidyl peptidase-4	DPP-9	DPP-8	FAP
1.75 nM	150 nM	189 nM	>10 μM

Solubility *

In vitro	DMSO	85 mg/mL (135.16 mM)
	Water	85 mg/mL (135.16 mM)
	Ethanol	14 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	7.95 mL	39.75 mL	79.51 mL
0.5 mM	1.59 mL	7.95 mL	15.9 mL
1 mM	0.8 mL	3.98 mL	7.95 mL
5 mM	0.16 mL	0.8 mL	1.59 mL

*The above data is based on the productmolecular weight 1257.72. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.