MDL 28170

Catalog No. A15303

MDL 28170是钙蛋白酶1（Ca2+依赖的半胱氨酸蛋白酶）的细胞可渗透选择性抑制剂，已与免疫细胞和神经元细胞的凋亡有关。

Product Citations

Barker BS, .et al. Screening for Efficacious Anticonvulsants and Neuroprotectants in Delayed Treatment Models of Organophosphate-induced Status Epilepticus, Neuroscience, 2019, Nov 26. pii: S0306-4522(19)30796-1 PMID: 31783100

Technical details

Catalog Num	A15303
M. Wt	382.45
Formula	C22H26N2O4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	88191-84-8
Synonyms	Calpain Inhibitor III
SMILES	CC(C)C(C(=O)NC(CC1=CC=CC=C1)C=O)NC(=O)OCC2=CC=CC=C2

Biological Activity

MDL 28170是钙蛋白酶1（Ca2+依赖的半胱氨酸蛋白酶）的细胞可渗透选择性抑制剂，已与免疫细胞和神经元细胞的凋亡有关。

Solubility *

In vitro	DMSO	69 mg/mL (180.41 mM)
	Water	Insoluble
	Ethanol	9 mg/mL (23.53 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.15 mL	130.74 mL	261.47 mL
0.5 mM	5.23 mL	26.15 mL	52.29 mL
1 mM	2.61 mL	13.07 mL	26.15 mL
5 mM	0.52 mL	2.61 mL	5.23 mL

*The above data is based on the productmolecular weight 382.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.