NU 1025

Catalog No. A15375

NU 1025是一种有效的聚（ADP-核糖）聚合酶（PARP）抑制剂，可增强L1210细胞中一系列机制多样的抗癌药的细胞毒性。

Technical details

Catalog Num	A15375
M. Wt	176.2
Formula	C9H8N2O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	90417-38-2
Synonyms	NU1025, NU-1025
SMILES	CC1=NC(=O)C2=C(N1)C(=CC=C2)O

Biological Activity

NU 1025是一种有效的聚（ADP-核糖）聚合酶（PARP）抑制剂，可增强L1210细胞中一系列机制多样的抗癌药的细胞毒性。

Targets

PARP
400 nM

Solubility *

In vitro (25°C)	DMSO	34 mg/mL (192.99 mM)
	Water	Insoluble
	Ethanol	Warmed: 6 mg/mL
In vivo	40% PEG 400+saline	17 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	56.75 mL	283.77 mL	567.54 mL
0.5 mM	11.35 mL	56.75 mL	113.51 mL
1 mM	5.68 mL	28.38 mL	56.75 mL
5 mM	1.14 mL	5.68 mL	11.35 mL

*The above data is based on the productmolecular weight 176.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.