Zidovudine

Catalog No. A15428

Zidovudine是一种核苷类似物逆转录酶抑制剂（NRTI），是一种用于治疗HIV/AIDS感染的抗逆转录病毒药物。叠氮胸苷降低了CRISPR介导的同源性定向修复（HDR）的效率。

Technical details

Catalog Num	A15428
M. Wt	267.3
Formula	C10H13N5O4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	30516-87-1
Synonyms	Azidothymidine, AZT, ZDV
SMILES	CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-]

Biological Activity

Targets

Reverse transcriptase

Solubility *

In vitro	DMSO	50 mg/mL (187.09 mM)
	Water	Warmed: 50 mg/mL (187.09 mM)
	Ethanol	Warmed: 17 mg/mL (63.61 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	37.41 mL	187.06 mL	374.11 mL
0.5 mM	7.48 mL	37.41 mL	74.82 mL
1 mM	3.74 mL	18.71 mL	37.41 mL
5 mM	0.75 mL	3.74 mL	7.48 mL

*The above data is based on the productmolecular weight 267.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.