CH-223191

Catalog No. A15436

CH-223191是Ah（Dioxin）受体的配体选择性拮抗剂。

Product Citations

Yukiko Sakakibara, .et al. Changes in uridine 5'-diphospho-glucuronosyltransferase 1A6 expression by histone deacetylase inhibitor valproic acid, Biopharm Drug Dispos, 2022, Oct;43(5):175-182 PMID: 36000181
Jie Tang, .et al. 2,2',4,4'-Tetrabromodiphenyl ether (BDE-47) activates Aryl hydrocarbon receptor (AhR) mediated ROS and NLRP3 inflammasome/p38 MAPK pathway inducing necrosis in cochlear hair cells, Ecotoxicol Environ Saf, 2021, Sep 15;221:112423 PMID: 34146985

Technical details

Catalog Num	A15436
M. Wt	333.39
Formula	C19H19N5O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	301326-22-7
Synonyms	CH223191
SMILES	CC1=CC=CC=C1N=NC2=CC(=C(C=C2)NC(=O)C3=CC=NN3C)C

Biological Activity

CH-223191是Ah（Dioxin）受体的配体选择性拮抗剂。

Targets

AhR
30 nM

Solubility *

In vitro	DMSO	61 mg/mL (182.96 mM)
	Water	Insoluble
	Ethanol	Warmed: 4 mg/mL (11.99 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29.99 mL	149.97 mL	299.95 mL
0.5 mM	6 mL	29.99 mL	59.99 mL
1 mM	3 mL	15 mL	29.99 mL
5 mM	0.6 mL	3 mL	6 mL

*The above data is based on the productmolecular weight 333.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.