R306465
Catalog No. A15437
R306465是一种新型的基于异羟肟酸酯的组蛋白脱乙酰基酶（HDAC）抑制剂，在临床前模型中具有针对实体和血液恶性肿瘤的广谱抗肿瘤活性。
- Mari Ishigami-Yuasa, .et al. Class IIb HDAC Inhibition Enhances the Inhibitory Effect of Am80, a Synthetic Retinoid, in Prostate Cancer, Biol Pharm Bull, 2019, 42, 448-452
| Catalog Num | A15437 |
|---|---|
| M. Wt | 413.45 |
| Formula | C19H19N5O4S |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 604769-01-9 |
| Synonyms | JNJ-16241199, JNJ16241199, JNJ 16241199 |
| SMILES | C1CN(CCN1C2=NC=C(C=N2)C(=O)NO)S(=O)(=O)C3=CC4=CC=CC=C4C=C3 |
R306465是一种新型的基于异羟肟酸酯的组蛋白脱乙酰基酶（HDAC）抑制剂，在临床前模型中具有针对实体和血液恶性肿瘤的广谱抗肿瘤活性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.19 mL | 120.93 mL | 241.87 mL |
| 0.5 mM | 4.84 mL | 24.19 mL | 48.37 mL |
| 1 mM | 2.42 mL | 12.09 mL | 24.19 mL |
| 5 mM | 0.48 mL | 2.42 mL | 4.84 mL |
*The above data is based on the productmolecular weight 413.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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