MI-773

Catalog No. A15440

MI-773是可用的MDM2拮抗剂，Ki为0.88 nM。

Technical details

Catalog Num	A15440
M. Wt	562.5
Formula	C29H34Cl2FN3O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1303607-60-4
Synonyms	SAR405838,MI 773, MI773
SMILES	CC(C)(C)C[C@H]1[C@@]2([C@H]([C@@H](N1)C(=O)NC3CCC(CC3)O)C4=C(C(=CC=C4)Cl)F)C5=C(C=C(C=C5)Cl)NC2=O

Biological Activity

MI-773是可用的MDM2拮抗剂，Ki为0.88 nM。

Targets

p53	MDM2
N/A	0.88 nM

Solubility *

In vitro	DMSO	93 mg/mL (165.33 mM)
	Water	Insoluble
	Ethanol	Warmed: 29 mg/mL (51.55 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.78 mL	88.89 mL	177.78 mL
0.5 mM	3.56 mL	17.78 mL	35.56 mL
1 mM	1.78 mL	8.89 mL	17.78 mL
5 mM	0.36 mL	1.78 mL	3.56 mL

*The above data is based on the productmolecular weight 562.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.