SGC 707

Catalog No. A15450

SGC 707是PRMT3的有效变构抑制剂（IC50 = 50 nM），其选择性是其他甲基转移酶和其他非表观遗传靶标的100倍以上。

Technical details

Catalog Num	A15450
M. Wt	298.3
Formula	C16H18N4O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1687736-54-4
Synonyms	SGC707, SGC-707
SMILES	C1CCN(C1)C(=O)CNC(=O)NC2=CC3=C(C=C2)C=NC=C3

Biological Activity

SGC 707是PRMT3的有效变构抑制剂（IC50 = 50 nM），其选择性是其他甲基转移酶和其他非表观遗传靶标的100倍以上。

Targets

PRMT3	PRMT3
31 nM	53 nM(Kd)

Solubility *

In vitro	DMSO	51 mg/mL (170.95 mM)
	Water	Insoluble
	Ethanol	Warmed: 51 mg/mL (170.95 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	33.52 mL	167.62 mL	335.23 mL
0.5 mM	6.7 mL	33.52 mL	67.05 mL
1 mM	3.35 mL	16.76 mL	33.52 mL
5 mM	0.67 mL	3.35 mL	6.7 mL

*The above data is based on the productmolecular weight 298.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.