ELR510444
Catalog No. A15455
ELR510444是一种新型的微管破坏剂；抑制MDA-MB-231细胞增殖，IC50为30.9 nM；而不是P-糖蛋白药物转运蛋白的底物，并在过量表达ΔIII-微管蛋白的细胞系中保留活性。
| Catalog Num | A15455 |
|---|---|
| M. Wt | 368.47 |
| Formula | C19H16N2O2S2 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1233948-35-0 |
| Synonyms | ELR-510444, ELR 510444 |
| SMILES | CC1=CC=C(S(NC2=C(C=CC(C3=CC=C(S3)C#N)=C2)C)(=O)=O)C=C1 |
ELR510444是一种新型的微管破坏剂；抑制MDA-MB-231细胞增殖，IC50为30.9 nM；而不是P-糖蛋白药物转运蛋白的底物，并在过量表达ΔIII-微管蛋白的细胞系中保留活性。
| In vitro | DMSO | 72 mg/mL (195.4 mM) | |
| Water | Insoluble | ||
| Ethanol | 24 mg/mL (65.13 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.14 mL | 135.7 mL | 271.39 mL |
| 0.5 mM | 5.43 mL | 27.14 mL | 54.28 mL |
| 1 mM | 2.71 mL | 13.57 mL | 27.14 mL |
| 5 mM | 0.54 mL | 2.71 mL | 5.43 mL |
*The above data is based on the productmolecular weight 368.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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