LY2409881

Catalog No. A15488

LY2409881是一种有效的选择性IKK2抑制剂,IC50为30 nM,选择性比IKK1和其他常见激酶高10倍以上。
Catalog Num A15488
M. Wt 594.43
Formula C24H32Cl4N6OS
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 946518-60-1
Synonyms LY-2409881, LY 2409881
SMILES CN1CCN(CC1)CCCNC2=NC=C(C(=N2)C3=CC4=C(C=CC=C4S3)C(=O)NC5CC5)Cl.Cl.Cl.Cl
LY2409881是一种有效的选择性IKK2抑制剂,IC50为30 nM,选择性比IKK1和其他常见激酶高10倍以上。
In vitro (25°C) DMSO Warmed: 18 mg/mL (30.28 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.82 mL 84.11 mL 168.23 mL
0.5 mM 3.36 mL 16.82 mL 33.65 mL
1 mM 1.68 mL 8.41 mL 16.82 mL
5 mM 0.34 mL 1.68 mL 3.36 mL

*The above data is based on the productmolecular weight 594.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.