BRD73954

Catalog No. A15489

BRD73954是一种小分子抑制剂，可有效抑制HDAC6和HDAC8（IC50分别为36和120 nM）。

Technical details

Catalog Num	A15489
M. Wt	284.3
Formula	C16H16N2O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1440209-96-0
Synonyms	BRD-73954, BRD 73954
SMILES	C1=CC=C(C=C1)CCNC(=O)C2=CC(=CC=C2)C(=O)NO

Biological Activity

BRD73954是一种小分子抑制剂，可有效抑制HDAC6和HDAC8（IC50分别为36和120 nM）。

Targets

HDAC6	HDAC8	HDAC2	HDAC4
36 nM	120 nM	9 μM	>33 μM

Solubility *

In vitro	DMSO	49 mg/mL (172.34 mM)
	Water	Insoluble
	Ethanol	Warmed: 8 mg/mL (28.13 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	35.17 mL	175.87 mL	351.74 mL
0.5 mM	7.03 mL	35.17 mL	70.35 mL
1 mM	3.52 mL	17.59 mL	35.17 mL
5 mM	0.7 mL	3.52 mL	7.03 mL

*The above data is based on the productmolecular weight 284.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.