CEP-37440

Catalog No. A15543

CEP-37440是一种新型的高效选择性FAK/ALK双重抑制剂,IC50为2.3 nM(FAK)和120 nM(ALK细胞在50%人血浆中的IC50。
Catalog Num A15543
M. Wt 580.12
Formula C30H38ClN7O3
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1391712-60-9
Synonyms CEP37440, CEP 37440
SMILES CNC(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C4=C(CC(CCC4)N5CCN(CC5)CCO)C=C3)OC
CEP-37440是一种新型的高效选择性FAK/ALK双重抑制剂,IC50为2.3 nM(FAK)和120 nM(ALK细胞在50%人血浆中的IC50。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.24 mL 86.19 mL 172.38 mL
0.5 mM 3.45 mL 17.24 mL 34.48 mL
1 mM 1.72 mL 8.62 mL 17.24 mL
5 mM 0.34 mL 1.72 mL 3.45 mL

*The above data is based on the productmolecular weight 580.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.