A-1210477

Catalog No. A15545

A-1210477是有效的选择性MCL-1抑制剂。A-1210477诱导内在凋亡的标志,并证明了多发性骨髓瘤和非小细胞肺癌细胞系的单药杀伤。
Catalog Num A15545
M. Wt 850.04
Formula C46H55N7O7S
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1668553-26-1
Synonyms A1210477
SMILES CC1=NN(C(=C1C2=CC=CC3=C2N(C(=C3CCCOC4=CC=CC5=CC=CC=C54)C(=O)O)CCN6CCOCC6)COC7=CC=C(C=C7)N8CCN(CC8)S(=O)(=O)N(C)C)C
A-1210477是有效的选择性MCL-1抑制剂。A-1210477诱导内在凋亡的标志,并证明了多发性骨髓瘤和非小细胞肺癌细胞系的单药杀伤。
Targets
MCL-1
26.2 nM
In vitro DMSO Warmed: 3 mg/mL (3.52 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 11.76 mL 58.82 mL 117.64 mL
0.5 mM 2.35 mL 11.76 mL 23.53 mL
1 mM 1.18 mL 5.88 mL 11.76 mL
5 mM 0.24 mL 1.18 mL 2.35 mL

*The above data is based on the productmolecular weight 850.04. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.