A-1210477
Catalog No. A15545
A-1210477是有效的选择性MCL-1抑制剂。A-1210477诱导内在凋亡的标志,并证明了多发性骨髓瘤和非小细胞肺癌细胞系的单药杀伤。
Catalog Num | A15545 |
---|---|
M. Wt | 850.04 |
Formula | C46H55N7O7S |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1668553-26-1 |
Synonyms | A1210477 |
SMILES | CC1=NN(C(=C1C2=CC=CC3=C2N(C(=C3CCCOC4=CC=CC5=CC=CC=C54)C(=O)O)CCN6CCOCC6)COC7=CC=C(C=C7)N8CCN(CC8)S(=O)(=O)N(C)C)C |
A-1210477是有效的选择性MCL-1抑制剂。A-1210477诱导内在凋亡的标志,并证明了多发性骨髓瘤和非小细胞肺癌细胞系的单药杀伤。
Targets
MCL-1 | ||||
26.2 nM |
In vitro | DMSO | Warmed: 3 mg/mL (3.52 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 11.76 mL | 58.82 mL | 117.64 mL |
0.5 mM | 2.35 mL | 11.76 mL | 23.53 mL |
1 mM | 1.18 mL | 5.88 mL | 11.76 mL |
5 mM | 0.24 mL | 1.18 mL | 2.35 mL |
*The above data is based on the productmolecular weight 850.04. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.