GSK503

Catalog No. A15549

GSK-503是一种有效的EZH2抑制剂，具有潜在的抗癌活性。

Technical details

Catalog Num	A15549
M. Wt	526.67
Formula	C31H38N6O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1346572-63-1
Synonyms	GSK-503, GSK 503
SMILES	CC1=CC(=C(C(=O)N1)CNC(=O)C2=C3C(=CN(C3=CC(=C2)C4=CN=C(C=C4)N5CCN(CC5)C)C(C)C)C)C

Biological Activity

GSK-503是一种有效的EZH2抑制剂，具有潜在的抗癌活性。

Targets

EZH2
8 nM

Solubility *

In vitro	DMSO	85 mg/mL (161.39 mM)
	Water	Insoluble
	Ethanol	Warmed: 22 mg/mL (41.77 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.99 mL	94.94 mL	189.87 mL
0.5 mM	3.8 mL	18.99 mL	37.97 mL
1 mM	1.9 mL	9.49 mL	18.99 mL
5 mM	0.38 mL	1.9 mL	3.8 mL

*The above data is based on the productmolecular weight 526.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.