IC 261

Catalog No. A15764

IC 261是CK1δ和CK1ε抑制剂。IC261对CK1的IC50为16 μM，对Cdk5的IC50为4.5 mM。

Technical details

Catalog Num	A15764
M. Wt	311.33
Formula	C18H17NO4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	186611-52-9
Synonyms	SU5607, SU 5607, SU-5607, IC261, IC-261
SMILES	COC1=CC(=C(C(=C1)OC)C=C2C3=CC=CC=C3NC2=O)OC

Biological Activity

IC 261是CK1δ和CK1ε抑制剂。IC261对CK1的IC50为16 μM，对Cdk5的IC50为4.5 mM。

Targets

CK1	CDK5
16 μM	4.5 mM

Solubility *

In vitro	DMSO	53 mg/mL (170.23 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.12 mL	160.6 mL	321.2 mL
0.5 mM	6.42 mL	32.12 mL	64.24 mL
1 mM	3.21 mL	16.06 mL	32.12 mL
5 mM	0.64 mL	3.21 mL	6.42 mL

*The above data is based on the productmolecular weight 311.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.