TP-0903

Catalog No. A15776

TP-0903是一种有效的选择性Axl激酶抑制剂，IC50为27 nM。

Technical details

Catalog Num	A15776
M. Wt	516.06
Formula	C24H30ClN7O2S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1341200-45-0
Synonyms	TP0903, TP 0903
SMILES	CN1CCN(CC1)CC2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4=CC=CC=C4S(=O)(=O)N(C)C)Cl

Biological Activity

TP-0903是一种有效的选择性Axl激酶抑制剂，IC50为27 nM。

Targets

Axl
27 nM

Solubility *

In vitro (25°C)	DMSO	Warmed: 3 mg/mL (5.81 mM)
	Water	Insoluble
	Ethanol	Warmed: 1 mg/mL (1.93 mM)
In vivo	0.5% CMC Na+1% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.38 mL	96.89 mL	193.78 mL
0.5 mM	3.88 mL	19.38 mL	38.76 mL
1 mM	1.94 mL	9.69 mL	19.38 mL
5 mM	0.39 mL	1.94 mL	3.88 mL

*The above data is based on the productmolecular weight 516.06. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.