TAK-063

Catalog No. A15799

TAK-063是一种高效,选择性和口服活性的PDE10A抑制剂,IC50为0.30 nM。选择性是其他PDE的15000倍以上。
Catalog Num A15799
M. Wt 428.42
Formula C23H17FN6O2
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1238697-26-1
Synonyms TAK 063, TAK063
SMILES COC1=CN(N=C(C1=O)C2=CC=NN2C3=CC=CC=C3)C4=C(C=C(C=C4)N5C=CC=N5)F
TAK-063是一种高效,选择性和口服活性的PDE10A抑制剂,IC50为0.30 nM。选择性是其他PDE的15000倍以上。
In vitro DMSO 73 mg/mL (170.39 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.34 mL 116.71 mL 233.42 mL
0.5 mM 4.67 mL 23.34 mL 46.68 mL
1 mM 2.33 mL 11.67 mL 23.34 mL
5 mM 0.47 mL 2.33 mL 4.67 mL

*The above data is based on the productmolecular weight 428.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.