Enasidenib

Catalog No. A15808

Enasidenib是一种有效的选择性IDH2抑制剂,具有潜在的抗癌活性(IDH2 =异柠檬酸脱氢酶2)。
  • Mohammed NadimSardoiwala, .et al. Hytrin loaded polydopamine-serotonin nanohybrid induces IDH2 mediated neuroprotective effect to alleviate Parkinson's disease, Materials Science and Engineering: C, 2021, Dec 24
Catalog Num A15808
M. Wt 473.38
Formula C19H17F6N7O
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1446502-11-9
Synonyms AG-221, AG 221, AG221
SMILES CC(C)(CNC1=NC(=NC(=N1)NC2=CC(=NC=C2)C(F)(F)F)C3=NC(=CC=C3)C(F)(F)F)O
Enasidenib是一种有效的选择性IDH2抑制剂,具有潜在的抗癌活性(IDH2 =异柠檬酸脱氢酶2)。
Targets
IDH2
12 nM
In vitro DMSO 90 mg/mL (190.12 mM)
Water Insoluble
Ethanol 90 mg/mL (190.12 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.12 mL 105.62 mL 211.25 mL
0.5 mM 4.22 mL 21.12 mL 42.25 mL
1 mM 2.11 mL 10.56 mL 21.12 mL
5 mM 0.42 mL 2.11 mL 4.22 mL

*The above data is based on the productmolecular weight 473.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.