I-BRD9

Catalog No. A15872

I-BRD9是一种有效的选择性BRD9抑制剂，pIC50为7.3，而对BRD4的pIC50为5.3。

Technical details

Catalog Num	A15872
M. Wt	497.55
Formula	C22H22F3N3O3S2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1714146-59-4
Synonyms	GSK602
SMILES	N=C(C(S1)=CC2=C1C(C3=CC=CC(C(F)(F)F)=C3)=CN(CC)C2=O)NC(CC4)CCS4(=O)=O

Biological Activity

I-BRD9是一种有效的选择性BRD9抑制剂，pIC50为7.3，而对BRD4的pIC50为5.3。

Targets

BRD9	BRD4
7.3(pIC50)	5.3(pIC50)

Solubility *

In vitro	DMSO	94 mg/mL (188.92 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.1 mL	100.49 mL	200.98 mL
0.5 mM	4.02 mL	20.1 mL	40.2 mL
1 mM	2.01 mL	10.05 mL	20.1 mL
5 mM	0.4 mL	2.01 mL	4.02 mL

*The above data is based on the productmolecular weight 497.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.