AZ6102
Catalog No. A15873
AZ6102是有效的TNKS1/2抑制剂,对其他PARP家族酶具有100倍的选择性,对DLD-1细胞中Wnt途径的抑制作用的IC50为5 nM。
Catalog Num | A15873 |
---|---|
M. Wt | 428.53 |
Formula | C25H28N6O |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1645286-75-4 |
Synonyms | AZ-6102, AZ 6102 |
SMILES | C[C@H]1CN(C2=NC=C(C3=CC=C(C4=NC(C(C=CN5C)=C5N4)=O)C=C3)C(C)=C2)C[C@@H](C)N1 |
AZ6102是有效的TNKS1/2抑制剂,对其他PARP家族酶具有100倍的选择性,对DLD-1细胞中Wnt途径的抑制作用的IC50为5 nM。
Targets
TNKS1 | TNKS2 | |||
In vitro | DMSO | 83 mg/mL (193.68 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 23.34 mL | 116.68 mL | 233.36 mL |
0.5 mM | 4.67 mL | 23.34 mL | 46.67 mL |
1 mM | 2.33 mL | 11.67 mL | 23.34 mL |
5 mM | 0.47 mL | 2.33 mL | 4.67 mL |
*The above data is based on the productmolecular weight 428.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.