VPS34-IN1

Catalog No. A15874

Vps34-IN1是一种有效且高度选择性的Vps34抑制剂，体外IC50为25 nM，不会显着抑制I类和II类PI3K的同工型。

Technical details

Catalog Num	A15874
M. Wt	425.91
Formula	C21H24ClN7O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1383716-33-3
Synonyms	PS34 IN1, VPS34IN1
SMILES	OC(C)(C)CNC(N=C1CC2CC2)=NC=C1C3=CC=NC(NC4=CC=NC(Cl)=C4)=N3

Biological Activity

Vps34-IN1是一种有效且高度选择性的Vps34抑制剂，体外IC50为25 nM，不会显着抑制I类和II类PI3K的同工型。

Targets

Vps34
25 nM

Solubility *

In vitro	DMSO	73 mg/mL (171.4 mM)
	Water	Insoluble
	Ethanol	73 mg/mL (171.4 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.48 mL	117.4 mL	234.79 mL
0.5 mM	4.7 mL	23.48 mL	46.96 mL
1 mM	2.35 mL	11.74 mL	23.48 mL
5 mM	0.47 mL	2.35 mL	4.7 mL

*The above data is based on the productmolecular weight 425.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.