SCH58261

Catalog No. A15886

SCH58261是一种有效的选择性A2a腺苷受体拮抗剂，对大鼠A2a和牛A2a的Ki分别为2.3 nM和2 nM。

Technical details

Catalog Num	A15886
M. Wt	345.36
Formula	C18H15N7O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	160098-96-4
Synonyms	SCH-58261, SCH 58261
SMILES	NC1=NC(N(CCC2=CC=CC=C2)N=C3)=C3C4=NC(C5=CC=CO5)=NN14

Biological Activity

SCH58261是一种有效的选择性A2a腺苷受体拮抗剂，对大鼠A2a和牛A2a的Ki分别为2.3 nM和2 nM。

Targets

bovine A2a	rat A2a
2.0 nM(Ki)	2.3 nM(Ki)

Solubility *

In vitro (25°C)	DMSO	61 mg/mL (176.63 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	4% DMSO40% PEG 300+4% Tween 80++ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	28.96 mL	144.78 mL	289.55 mL
0.5 mM	5.79 mL	28.96 mL	57.91 mL
1 mM	2.9 mL	14.48 mL	28.96 mL
5 mM	0.58 mL	2.9 mL	5.79 mL

*The above data is based on the productmolecular weight 345.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.