ORY-1001 (RG-6016)

Catalog No. A15893

ORY-1001 (RG-6016)是一种活性的选择性赖氨酸脱甲基酶LSD1/KDM1A抑制剂，IC50 <20 nM，对相关FAD依赖性氨氧化酶具有高选择性。

Technical details

Catalog Num	A15893
M. Wt	303.27
Formula	C15H22N2.2HCl
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1431326-61-2
Synonyms	RG6016, RG-6016
SMILES	NC1CCC(N[C@@H]2C[C@H]2C3=CC=CC=C3)CC1.Cl.Cl

Biological Activity

ORY-1001 (RG-6016)是一种活性的选择性赖氨酸脱甲基酶LSD1/KDM1A抑制剂，IC50 <20 nM，对相关FAD依赖性氨氧化酶具有高选择性。

Targets

LSD1/KDM1A
20 nM

Solubility *

In vitro	DMSO	4 mg/mL (13.18 mM)
	Water	53 mg/mL (174.76 mM)
	Ethanol	Warmed: 3 mg/mL (9.89 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.97 mL	164.87 mL	329.74 mL
0.5 mM	6.59 mL	32.97 mL	65.95 mL
1 mM	3.3 mL	16.49 mL	32.97 mL
5 mM	0.66 mL	3.3 mL	6.59 mL

*The above data is based on the productmolecular weight 303.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.