Dyngo-4a

Catalog No. A15915

Dyngo-4a is a potent dynamin inhibitor with IC50 of 0.38 uM, 1.1uM, and 2.3 uM for DynI (brain), DynI (rec), and DynII (rec), respectively.

Technical details

Catalog Num	A15915
M. Wt	338.31
Formula	C18H14N2O5
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1256493-34-1
Synonyms
SMILES	OC1=CC(O)=C(O)C=C1/C([H])=N/N=C(O)/C2=CC3=CC=CC=C3C=C2O

Biological Activity

Dyngo-4a is a potent dynamin inhibitor with IC50 of 0.38 uM, 1.1uM, and 2.3 uM for DynI (brain), DynI (rec), and DynII (rec), respectively.

Targets

DynI (brain)	DynI (rec)	DynII (rec)
0.38 μM	1.1 μM	2.3 μM

Solubility *

In vitro	DMSO	66 mg/mL (195.08 mM)
	Water	Insoluble
	Ethanol	Warmed: 1 mg/mL (2.95 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29.56 mL	147.79 mL	295.59 mL
0.5 mM	5.91 mL	29.56 mL	59.12 mL
1 mM	2.96 mL	14.78 mL	29.56 mL
5 mM	0.59 mL	2.96 mL	5.91 mL

*The above data is based on the productmolecular weight 338.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.