AMI-1

Catalog No. A15916

AMI-1是一种有效的特异组蛋白甲基转移酶（HMT）抑制剂，对酵母Hmt1p和人PRMT1的IC50分别为3.0 uM和8.8 uM。

Technical details

Catalog Num	A15916
M. Wt	548.45
Formula	C21H14N2Na2O9S2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	20324-87-2
Synonyms	AMI 1, AMI1, AMI-1 disodium salt
SMILES	O=C(NC1=CC2=CC(S(=O)([O-])=O)=CC(O)=C2C=C1)NC3=CC4=CC(S(=O)([O-])=O)=CC(O)=C4C=C3.[Na+].[Na+]

Biological Activity

AMI-1是一种有效的特异组蛋白甲基转移酶（HMT）抑制剂，对酵母Hmt1p和人PRMT1的IC50分别为3.0 uM和8.8 uM。

Targets

yeast Hmt1p	human PRMT1
3.0 μM	8.8 μM

Solubility *

In vitro (25°C)	DMSO	Warmed: 89 mg/mL (162.27 mM)
	Water	9 mg/mL (16.41 mM)
	Ethanol	Insoluble
In vivo	PBS	20 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.23 mL	91.17 mL	182.33 mL
0.5 mM	3.65 mL	18.23 mL	36.47 mL
1 mM	1.82 mL	9.12 mL	18.23 mL
5 mM	0.36 mL	1.82 mL	3.65 mL

*The above data is based on the productmolecular weight 548.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.