ACY-738

Catalog No. A15934

ACY-738是一种有效的选择性HDAC6抑制剂，具有改善的脑生物利用度。ACY-738抑制HDAC6的纳摩尔浓度低，选择性比I类HDAC高60到1500倍。

Product Citations

Guang Bai, .et al. Chapter 1 - Epigenetic Tools in Chronic Pain Studies, Epigenetics of Chronic Pain, 2019, Pages 1-48

Technical details

Catalog Num	A15934
M. Wt	270.29
Formula	C14H14N4O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1375465-91-0
Synonyms	ACY 738, ACY738
SMILES	O=C(C1=CN=C(NC2(C3=CC=CC=C3)CC2)N=C1)NO

Biological Activity

ACY-738是一种有效的选择性HDAC6抑制剂，具有改善的脑生物利用度。ACY-738抑制HDAC6的纳摩尔浓度低，选择性比I类HDAC高60到1500倍。

Solubility *

In vitro	DMSO	46 mg/mL (170.18 mM)
	Water	Insoluble
	Ethanol	1 mg/mL (3.69 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	37 mL	184.99 mL	369.97 mL
0.5 mM	7.4 mL	37 mL	73.99 mL
1 mM	3.7 mL	18.5 mL	37 mL
5 mM	0.74 mL	3.7 mL	7.4 mL

*The above data is based on the productmolecular weight 270.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.