Olmutinib (HM61713)

Catalog No. A15976

Olmutinib (HM61713)是Bruton酪氨酸激酶（BTK）的有效小分子抑制剂。

Technical details

Catalog Num	A15976
M. Wt	486.59
Formula	C26H26N6O2S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1353550-13-6
Synonyms	HM 61713, HM-61713, BI-1482694, BI1482694, BI 1482694
SMILES	C=CC(NC1=CC=CC(OC2=C3C(C=CS3)=NC(NC4=CC=C(N5CCN(C)CC5)C=C4)=N2)=C1)=O

Biological Activity

Olmutinib (HM61713)是Bruton酪氨酸激酶（BTK）的有效小分子抑制剂。

Targets

mutant EGFR

Solubility *

In vitro	DMSO	95 mg/mL (195.23 mM)
	Water	Insoluble
	Ethanol	23 mg/mL (47.26 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.55 mL	102.76 mL	205.51 mL
0.5 mM	4.11 mL	20.55 mL	41.1 mL
1 mM	2.06 mL	10.28 mL	20.55 mL
5 mM	0.41 mL	2.06 mL	4.11 mL

*The above data is based on the productmolecular weight 486.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.