SKI-II

Catalog No. A15988

SKI-II是鞘氨醇激酶的选择性非脂质抑制剂（IC50 = 0.5 uM）。

Technical details

Catalog Num	A15988
M. Wt	302.78
Formula	C15H11ClN2OS
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	312636-16-1
Synonyms	SKI II, Sphingosine kinase inhibitor II
SMILES	OC1=CC=C(NC2=NC(C3=CC=C(Cl)C=C3)=CS2)C=C1

Biological Activity

SKI-II是鞘氨醇激酶的选择性非脂质抑制剂（IC50 = 0.5 uM）。

Targets

S1P receptor
0.5 μM

Solubility *

In vitro	DMSO	57 mg/mL (188.25 mM)
	Water	Insoluble
	Ethanol	57 mg/mL (188.25 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	33.03 mL	165.14 mL	330.27 mL
0.5 mM	6.61 mL	33.03 mL	66.05 mL
1 mM	3.3 mL	16.51 mL	33.03 mL
5 mM	0.66 mL	3.3 mL	6.61 mL

*The above data is based on the productmolecular weight 302.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.