PQR309 (Bimiralisib)

Catalog No. A15992

PQR309是磷酸肌醇3激酶（PI3K）的口服生物利用泛抑制剂，是雷帕霉素哺乳动物靶标（mTOR）的抑制剂，具有潜在的抗肿瘤活性。

Technical details

Catalog Num	A15992
M. Wt	411.39
Formula	C17H20F3N7O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1225037-39-7
Synonyms	PQR-309, PQR 309
SMILES	NC1=NC=C(C2=NC(N3CCOCC3)=NC(N4CCOCC4)=N2)C(C(F)(F)F)=C1

Biological Activity

PQR309是磷酸肌醇3激酶（PI3K）的口服生物利用泛抑制剂，是雷帕霉素哺乳动物靶标（mTOR）的抑制剂，具有潜在的抗肿瘤活性。

Solubility *

In vitro	DMSO	6 mg/mL (14.58 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.31 mL	121.54 mL	243.08 mL
0.5 mM	4.86 mL	24.31 mL	48.62 mL
1 mM	2.43 mL	12.15 mL	24.31 mL
5 mM	0.49 mL	2.43 mL	4.86 mL

*The above data is based on the productmolecular weight 411.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

PQR309 (Bimiralisib)

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions