OF-1

Catalog No. A16000

OF-1是BRPF溴结构域的化学探针。OF-1已显示以100 nM的KD（ITC）结合到BRPF1B，以500 nM的KD（ITC）结合到BRPF2和以2.4 uM的KD（ITC）结合到BRPF3。

Technical details

Catalog Num	A16000
M. Wt	440.31
Formula	C17H18BrN3O4S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	19973-83-4
Synonyms	OF1, OF 1
SMILES	O=S(C1=CC=C(Br)C=C1C)(NC2=C(OC)C=C(N3C)C(N(C)C3=O)=C2)=O

Biological Activity

OF-1是BRPF溴结构域的化学探针。OF-1已显示以100 nM的KD（ITC）结合到BRPF1B，以500 nM的KD（ITC）结合到BRPF2和以2.4 uM的KD（ITC）结合到BRPF3。

Solubility *

In vitro (25°C)	DMSO	Warmed: 72 mg/mL (163.52 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5%DMSO+30%PEG300+5%Tween-80+ddH2O	2 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.71 mL	113.56 mL	227.11 mL
0.5 mM	4.54 mL	22.71 mL	45.42 mL
1 mM	2.27 mL	11.36 mL	22.71 mL
5 mM	0.45 mL	2.27 mL	4.54 mL

*The above data is based on the productmolecular weight 440.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

OF-1

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions