KPT 335

Catalog No. A16078

KPT 335是口服可生物利用的核出口选择性抑制剂(SINE)。
Catalog Num A16078
M. Wt 442.32
Formula C18H12F6N6O
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1392136-43-4
Synonyms Verdinexor
SMILES O=C(NNC1=NC=CC=C1)/C=C\N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2
KPT 335是口服可生物利用的核出口选择性抑制剂(SINE)。
Targets
CRM1
In vitro (25°C) DMSO 83 mg/mL (187.65 mM)
Water Insoluble
Ethanol Warmed: 10 mg/mL
In vivo 5% DMSO+corn oil 14 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.61 mL 113.04 mL 226.08 mL
0.5 mM 4.52 mL 22.61 mL 45.22 mL
1 mM 2.26 mL 11.3 mL 22.61 mL
5 mM 0.45 mL 2.26 mL 4.52 mL

*The above data is based on the productmolecular weight 442.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.