KPT 335
Catalog No. A16078
KPT 335是口服可生物利用的核出口选择性抑制剂(SINE)。
Catalog Num | A16078 |
---|---|
M. Wt | 442.32 |
Formula | C18H12F6N6O |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1392136-43-4 |
Synonyms | Verdinexor |
SMILES | O=C(NNC1=NC=CC=C1)/C=C\N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2 |
KPT 335是口服可生物利用的核出口选择性抑制剂(SINE)。
Targets
CRM1 | ||||
In vitro (25°C) | DMSO | 83 mg/mL (187.65 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 10 mg/mL | ||
In vivo | 5% DMSO+corn oil | 14 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.61 mL | 113.04 mL | 226.08 mL |
0.5 mM | 4.52 mL | 22.61 mL | 45.22 mL |
1 mM | 2.26 mL | 11.3 mL | 22.61 mL |
5 mM | 0.45 mL | 2.26 mL | 4.52 mL |
*The above data is based on the productmolecular weight 442.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.