MK-4101

Catalog No. A16111

MK-4101是Hedgehog通路的有效和选择性抑制剂。

Technical details

Catalog Num	A16111
M. Wt	493.48
Formula	C24H24F5N5O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	935273-79-3
Synonyms	MK 4101, MK4101
SMILES	FC(C1=CC=CC=C1C2=NN=C(C34CCC(C5=NOC(C6CC(F)(F)C6)=N5)(CC4)CC3)N2C)(F)F

Biological Activity

MK-4101是Hedgehog通路的有效和选择性抑制剂。

Targets

SMO

Solubility *

In vitro	DMSO	89 mg/mL (180.35 mM)
	Water	Insoluble
	Ethanol	55 mg/mL (111.45 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.26 mL	101.32 mL	202.64 mL
0.5 mM	4.05 mL	20.26 mL	40.53 mL
1 mM	2.03 mL	10.13 mL	20.26 mL
5 mM	0.41 mL	2.03 mL	4.05 mL

*The above data is based on the productmolecular weight 493.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.