Sivelestat sodium hydrate (ONO-5046 sodium hydrate)

Catalog No. A16137

Sivelestat sodium hydrate (ONO-5046 sodium hydrate)是人嗜中性粒细胞弹性蛋白酶的竞争性抑制剂，还抑制从兔，大鼠，仓鼠和小鼠获得的白细胞弹性蛋白酶。

Technical details

Catalog Num	A16137
M. Wt	528.51
Formula	C20H21N2O7S.4H2O.Na
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	201677-61-4
Synonyms	ONO5046-Na, EI546 sodium, LY544349 sodium
SMILES	O=S(C1=CC=C(OC(C(C)(C)C)=O)C=C1)(NC2=C(C(NCC([O-])=O)=O)C=CC=C2)=O.[Na+].O.O.O.O

Biological Activity

Sivelestat sodium hydrate (ONO-5046 sodium hydrate)是人嗜中性粒细胞弹性蛋白酶的竞争性抑制剂，还抑制从兔，大鼠，仓鼠和小鼠获得的白细胞弹性蛋白酶。

Targets

neutrophil elastase

Solubility *

In vitro	DMSO	91 mg/mL (172.18 mM)
	Water	Insoluble
	Ethanol	91 mg/mL (172.18 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.92 mL	94.61 mL	189.21 mL
0.5 mM	3.78 mL	18.92 mL	37.84 mL
1 mM	1.89 mL	9.46 mL	18.92 mL
5 mM	0.38 mL	1.89 mL	3.78 mL

*The above data is based on the productmolecular weight 528.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.